Small Molecules Promote Selective Denaturation and Degradation of Tubulin Heterodimers through a Low-Barrier Hydrogen Bond | Journal of Medicinal Chemistry
Acute coronary syndromes in diabetic patients, outcome, revascularization, and antithrombotic therapy - ScienceDirect
Discovery of a Highly Selective, Brain-Penetrant Aminopyrazole LRRK2 Inhibitor | ACS Medicinal Chemistry Letters
Stabilization of Nanoparticles Produced by Hydrogenation of Palladium–N-Heterocyclic Carbene Complexes on the Surface of Graphene and Implications in Catalysis | ACS Omega
Structure-Guided Modification of Heterocyclic Antagonists of the P2Y14 Receptor | Journal of Medicinal Chemistry
Discovery of a 3-(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity | Journal of Medicinal Chemistry
LogD Contributions of Substituents Commonly Used in Medicinal Chemistry | ACS Medicinal Chemistry Letters
Discovery of Potent and Selective PI3Kγ Inhibitors | Journal of Medicinal Chemistry
ACS Medicinal Chemistry Letters | Vol 11, No 11
Discovery of a Selective Phosphoinositide-3-Kinase (PI3K)-γ Inhibitor (IPI-549) as an Immuno-Oncology Clinical Candidate | ACS Medicinal Chemistry Letters
Synthesis of Thymoquinone–Artemisinin Hybrids: New Potent Antileukemia, Antiviral, and Antimalarial Agents | ACS Medicinal Chemistry Letters
Forging Odd-Membered Rings: Palladium-Catalyzed Asymmetric Cycloadditions of Trimethylenemethane | Accounts of Chemical Research
Design, Synthesis, and Structure–Activity Relationship Optimization of Pyrazolopyrimidine Amide Inhibitors of Phosphoinositide 3-Kinase γ (PI3Kγ) | Journal of Medicinal Chemistry
Structure and Mechanism-Guided Design of Dual Serine/Metallo-Carbapenemase Inhibitors | Journal of Medicinal Chemistry
Rational Alteration of Pharmacokinetics of Chiral Fluorinated and Deuterated Derivatives of Emixustat for Retinal Therapy | Journal of Medicinal Chemistry
The “Cyclopropyl Fragment” is a Versatile Player that Frequently Appears in Preclinical/Clinical Drug Molecules | Journal of Medicinal Chemistry
Discovery of Novel BRD4 Ligand Scaffolds by Automated Navigation of the Fragment Chemical Space | Journal of Medicinal Chemistry
Discovery of Highly Isoform Selective Orally Bioavailable Phosphoinositide 3-Kinase (PI3K)-γ Inhibitors | Journal of Medicinal Chemistry
Design and Synthesis of Potent Quinazolines as Selective β-Glucocerebrosidase Modulators | Journal of Medicinal Chemistry
Synthesis and Cell-Based Activity of a Potent and Selective Protein Tyrosine Phosphatase 1B Inhibitor Prodrug | Journal of Medicinal Chemistry
Multifunctional Carrier Based on Halloysite/Laponite Hybrid Hydrogel for Kartogenin Delivery | ACS Medicinal Chemistry Letters
Discovery of Potent and Selective 7-Azaindole Isoindolinone-Based PI3Kγ Inhibitors | ACS Medicinal Chemistry Letters
Discovery of Highly Selective Inhibitors of the Immunoproteasome Low Molecular Mass Polypeptide 2 (LMP2) Subunit | ACS Medicinal Chemistry Letters
Collaborative Virtual Screening Identifies a 2-Aryl-4-aminoquinazoline Series with Efficacy in an In Vivo Model of Trypanosoma cruzi Infection | Journal of Medicinal Chemistry
